This debate focuses on discussing the current advances in Sotos Syndrome research and exploring future directions that could benefit the affected community. From genetic studies to clinical and therapeutic research, this debate addresses the latest developments in the field and emerging areas of investigation.

1. Genetics of Sotos Syndrome: What are the latest discoveries in identifying genes associated with Sotos Syndrome beyond NSD1? What role do these genes play in the pathophysiology of the disease?
2. Animal Models and Preclinical Studies: What advances have been made in developing animal models to study Sotos Syndrome? How are these models contributing to our understanding of the disease and the development of new therapies?
3. Clinical Research: What clinical trials are ongoing or planned to evaluate potential treatments for Sotos Syndrome? What preliminary results have been obtained, and what are the expectations for the future?
4. Exploration of Molecular Pathways: What molecular pathways are being investigated as potential therapeutic targets in Sotos Syndrome? How could these pathways offer new opportunities for treatment development?
5. Epidemiological Studies: What do we know about the prevalence and incidence of Sotos Syndrome in different populations? What genetic and environmental factors could influence the phenotypic expression of the disease?
6. Psychosocial Aspects of Research: How are psychosocial aspects addressed in Sotos Syndrome research? What studies are exploring the emotional and social impact of living with the disease? 

Objectives:

– Share information about the latest research in Sotos Syndrome.

– Identify key areas of research requiring further attention.

– Establish collaborations between researchers, healthcare professionals, and the affected community.

– Explore new opportunities to improve diagnosis, treatment, and support for individuals with Sotos Syndrome.